Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation.
<p><strong>Background</strong> CRISPR-Cas9 gene-editing technology has facilitated the generation of knockout mice, providing an alternative to cumbersome and time-consuming traditional embryonic stem cell-based methods. An earlier study reported up to 16% efficiency in generating...
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
BioMed Central
2019
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