Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.

OBJECTIVES: This study sought to investigate the role of secretory phospholipase A2 (sPLA2)-IIA in cardiovascular disease. BACKGROUND: Higher circulating levels of sPLA2-IIA mass or sPLA2 enzyme activity have been associated with increased risk of cardiovascular events. However, it is not clear if t...

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Main Authors: Holmes, M, Simon, T, Exeter, H, Folkersen, L, Asselbergs, F, Guardiola, M, Cooper, J, Palmen, J, Hubacek, J, Carruthers, K, Horne, B, Brunisholz, K, Mega, J, van Iperen, E, Li, M, Leusink, M, Trompet, S, Verschuren, J, Hovingh, G, Dehghan, A, Nelson, C, Kotti, S, Danchin, N, Scholz, M, Haase, C
Format: Journal article
Language:English
Published: 2013