Molecular determinants of chromatin accessibility at CpG islands in mouse embryonic stem cells

<p>In eukaryotic cells, transcription factors and polymerases must access DNA in the context of nucleosomes and chromatin. The accessibility of DNA sequences to such <em>trans</em>-acting factors is an important feature of gene regulatory elements, including promoters. In vertebrat...

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Bibliographic Details
Main Author: King, H
Other Authors: Klose, R
Format: Thesis
Published: 2017
Subjects: