Intragenic enhancers act as alternative promoters.

A substantial amount of organismal complexity is thought to be encoded by enhancers which specify the location, timing, and levels of gene expression. In mammals there are more enhancers than promoters which are distributed both between and within genes. Here we show that activated, intragenic enhan...

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Autors principals: Kowalczyk, MS, Hughes, J, Garrick, D, Lynch, MD, Sharpe, J, Sloane-Stanley, J, McGowan, S, De Gobbi, M, Hosseini, M, Vernimmen, D, Brown, J, Gray, N, Collavin, L, Gibbons, R, Flint, J, Taylor, S, Buckle, V, Milne, T, Wood, W, Higgs, D
Format: Journal article
Idioma:English
Publicat: Cell Press 2012