Intragenic enhancers act as alternative promoters.

A substantial amount of organismal complexity is thought to be encoded by enhancers which specify the location, timing, and levels of gene expression. In mammals there are more enhancers than promoters which are distributed both between and within genes. Here we show that activated, intragenic enhan...

Description complète

Détails bibliographiques
Auteurs principaux: Kowalczyk, MS, Hughes, J, Garrick, D, Lynch, MD, Sharpe, J, Sloane-Stanley, J, McGowan, S, De Gobbi, M, Hosseini, M, Vernimmen, D, Brown, J, Gray, N, Collavin, L, Gibbons, R, Flint, J, Taylor, S, Buckle, V, Milne, T, Wood, W, Higgs, D
Format: Journal article
Langue:English
Publié: Cell Press 2012