Stereoselective reduction of chiral 2-furoic acid derivatives using group I metals in ammonia
A series of chiral auxiliaries have been attached to 2-furoic acid and 3-methyl-2-furoic acid. The performance of these auxiliaries in the Birch reduction was assessed and it was found that placing a C-3 methyl group on the heterocycle was essential for good stereoselectivity. Using bis(methoxymethy...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2000
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