Structural genomics of histone tail recognition.
SUMMARY: The structural genomics of histone tail recognition web server is an open access resource that presents within mini articles all publicly available experimental structures of histone tails in complex with human proteins. Each article is composed of interactive 3D slides that dissect the st...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Oxford University Press
2010
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| _version_ | 1797068989236510720 |
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| author | Wang, M Mok, M Harper, H Lee, W Min, J Knapp, S Oppermann, U Marsden, B Schapira, M |
| author_facet | Wang, M Mok, M Harper, H Lee, W Min, J Knapp, S Oppermann, U Marsden, B Schapira, M |
| author_sort | Wang, M |
| collection | OXFORD |
| description | SUMMARY: The structural genomics of histone tail recognition web server is an open access resource that presents within mini articles all publicly available experimental structures of histone tails in complex with human proteins. Each article is composed of interactive 3D slides that dissect the structural mechanism underlying the recognition of specific sequences and histone marks. A concise text html-linked to interactive graphics guides the reader through the main features of the interaction. This resource can be used to analyze and compare binding modes across multiple histone recognition modules, to evaluate the chemical tractability of binding sites involved in epigenetic signaling and design small molecule inhibitors. AVAILABILITY: http://www.thesgc.org/resources/histone_tails/ CONTACT: matthieu.schapira@utoronto.ca SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. |
| first_indexed | 2024-03-06T22:17:58Z |
| format | Journal article |
| id | oxford-uuid:540d4377-12ca-4604-ae36-5beaffb96c1e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:17:58Z |
| publishDate | 2010 |
| publisher | Oxford University Press |
| record_format | dspace |
| spelling | oxford-uuid:540d4377-12ca-4604-ae36-5beaffb96c1e2022-03-26T16:35:29ZStructural genomics of histone tail recognition.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:540d4377-12ca-4604-ae36-5beaffb96c1eEnglishSymplectic Elements at OxfordOxford University Press2010Wang, MMok, MHarper, HLee, WMin, JKnapp, SOppermann, UMarsden, BSchapira, M SUMMARY: The structural genomics of histone tail recognition web server is an open access resource that presents within mini articles all publicly available experimental structures of histone tails in complex with human proteins. Each article is composed of interactive 3D slides that dissect the structural mechanism underlying the recognition of specific sequences and histone marks. A concise text html-linked to interactive graphics guides the reader through the main features of the interaction. This resource can be used to analyze and compare binding modes across multiple histone recognition modules, to evaluate the chemical tractability of binding sites involved in epigenetic signaling and design small molecule inhibitors. AVAILABILITY: http://www.thesgc.org/resources/histone_tails/ CONTACT: matthieu.schapira@utoronto.ca SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. |
| spellingShingle | Wang, M Mok, M Harper, H Lee, W Min, J Knapp, S Oppermann, U Marsden, B Schapira, M Structural genomics of histone tail recognition. |
| title | Structural genomics of histone tail recognition. |
| title_full | Structural genomics of histone tail recognition. |
| title_fullStr | Structural genomics of histone tail recognition. |
| title_full_unstemmed | Structural genomics of histone tail recognition. |
| title_short | Structural genomics of histone tail recognition. |
| title_sort | structural genomics of histone tail recognition |
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