Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria.

Chloroquine (CQ)-resistant Plasmodium vivax malaria was first reported 12 years ago, nearly 30 years after the recognition of CQ-resistant P. falciparum. Loss of CQ efficacy now poses a severe problem for the prevention and treatment of both diseases. Mutations in a digestive vacuole protein encoded...

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Main Authors: Nomura, T, Carlton, J, Baird, J, del Portillo, H, Fryauff, D, Rathore, D, Fidock, D, Su, X, Collins, W, McCutchan, T, Wootton, J, Wellems, T
格式: Journal article
语言:English
出版: 2001