Nonsense-mediated mRNA decay: Target genes and functional diversification of effectors.

Recent genome-wide identification of nonsense-mediated mRNA decay (NMD) targets in yeast, fruitfly and human cells has provided insight into the biological functions and evolution of this mRNA quality control mechanism, revealing that NMD post-transcriptionally regulates an important fraction of the...

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Bibliographic Details
Main Authors: Rehwinkel, J, Raes, J, Izaurralde, E
Format: Journal article
Language:English
Published: 2006