Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17//RAC1-mediated activation of NADPH oxidases

Obesity is associated with changes in the secretome of adipose tissue (AT), which affects the vasculature through endocrine and paracrine mechanisms. Wingless-related integration site 5A (WNT5A) and secreted frizzled-related protein 5 (SFRP5), adipokines that regulate noncanonical Wnt signaling, are...

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Bibliographic Details
Main Authors:	Akoumianakis, I, Sanna, F, Margaritis, M, Badi, I, Akawi, N, Herdman, L, Coutinho, P, Fagan, H, Antonopoulos, A, Oikonomou, E, Thomas, S, Chiu, A, Chuaiphichai, S, Kotanidis, C, Christodoulides, C, Petrou, M, Krasopoulos, G, Sayeed, R, Lv, L, Hale, A, Kararoudi, M, McNeill, E, Douglas, G, George, S, Tousoulis, D, Channon, K, Antoniades, C
Format:	Journal article
Published:	American Association for the Advancement of Science 2019

Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17//RAC1-mediated activation of NADPH oxidases

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