Loss of viral control in early HIV-1 infection is temporally associated with sequential escape from CD8+ T cell responses and decrease in HIV-1-specific CD4+ and CD8+ T cell frequencies.

Loss of viral control in early HIV-1 infection is temporally associated with sequential escape from CD8+ T cell responses and decrease in HIV-1-specific CD4+ and CD8+ T cell frequencies.

The outcome of human immunodeficiency virus type 1 (HIV-1) infection is related to the set-point plasma virus load (pVL) that emerges after primary HIV-1 infection (PHI). This set-point pVL generally remains stable but eventually increases with progression to disease. However, the events leading to...

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Bibliographic Details
Main Authors: Oxenius, A, Price, D, Trkola, A, Edwards, C, Gostick, E, Zhang, H, Easterbrook, P, Tun, T, Johnson, A, Waters, A, Holmes, E, Phillips, R
Format: Journal article
Language:English
Published: 2004

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