Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.

BACKGROUND: The HLA-B*35-Px allele has been associated with rapid disease progression in HIV-1 infection, in contrast to the HLA-B*35-Py allele. METHODOLOGY/PRINCIPAL FINDINGS: Immune responses to two HLA-B*35 restricted HIV-1 specific CTL epitopes and their variants were followed longitudinally du...

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Bibliographic Details
Main Authors: Willberg, C, Garrison, K, Jones, R, Meiklejohn, D, Spotts, G, Liegler, T, Ostrowski, M, Karlsson, A, Hecht, F, Nixon, D
Format: Journal article
Language:English
Published: Public Library of Science 2010