Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas.

BACKGROUND and AIMS: According to the somatic mutation theory, monoclonal colorectal lesions arise from sequential mutations in the progeny of a single stem cell. However, studies in a sex chromosome mixoploid mosaic (XO/XY) patient indicated that colorectal adenomas were polyclonal. We assessed ade...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Thirlwell, C, Will, O, Domingo, E, Graham, T, McDonald, SA, Oukrif, D, Jeffrey, R, Gorman, M, Rodriguez-Justo, M, Chin-Aleong, J, Clark, S, Novelli, MR, Jankowski, J, Wright, N, Tomlinson, I, Leedham, S
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2010

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