Imaging the DNA damage response with PET and SPECT

DNA integrity is constantly challenged by endogenous and exogenous factors that can alter the DNA sequence, leading to mutagenesis, aberrant transcriptional activity, and cytotoxicity. Left unrepaired, damaged DNA can ultimately lead to the development of cancer. To overcome this threat, a series of...

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Bibliographic Details
Main Authors: Knight, J, Koustoulidou, S, Cornelissen, B
Format: Journal article
Published: Springer Berlin Heidelberg 2017