Gene transfer of a broad spectrum CC-chemokine inhibitor reduces vein graft atherosclerosis in apolipoprotein E-knockout mice.

BACKGROUND: Accelerated atherosclerosis is a major cause of vein graft failure after bypass surgery. Several CC-chemokines (CC-CKs) mediate monocyte/macrophage recruitment in native atherosclerotic plaques; we hypothesized that CC-CKs may be critical in the development of accelerated atherosclerosi...

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Bibliographic Details
Main Authors: Ali, Z, Bursill, C, Hu, Y, Choudhury, R, Xu, Q, Greaves, D, Channon, K
Format: Journal article
Language:English
Published: 2005