Human TGF-β1 deficiency causes severe inflammatory bowel disease and encephalopathy

Transforming growth factor (TGF)-β1 (encoded by TGFB1) is the prototypic member of the TGF-β family of 33 proteins that orchestrate embryogenesis, development and tissue homeostasis1,2. Following its discovery 3 , enormous interest and numerous controversies have emerged about the role of TGF-β in c...

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Bibliographic Details
Main Authors: Kotlarz, D, Marquardt, B, Barøy, T, Lee, W, Konnikova, L, Hollizeck, S, Magg, T, Lehle, A, Walz, C, Borggraefe, I, Hauck, F, Bufler, P, Conca, R, Wall, S, Schumacher, E, Misceo, D, Frengen, E, Bentsen, B, Uhlig, H, Hopfner, K, Muise, A, Snapper, S, Strømme, P, Klein, C
Format: Journal article
Language:English
Published: Springer Nature 2018