Combination therapy with zidovudine and didanosine selects for drug-resistant human immunodeficiency virus type 1 strains with unique patterns of pol gene mutations.

Drug resistance conferred by specific human immunodeficiency virus type 1 (HIV-1) pol gene mutations has been associated with clinical progression in HIV-infected patients receiving anti-retroviral therapy. This study examined drug susceptibilities and pol mutations of HIV-1 strains from patients tr...

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Bibliographic Details
Main Authors: Shafer, R, Kozal, M, Winters, M, Iversen, A, Katzenstein, D, Ragni, M, Meyer, W, Gupta, P, Rasheed, S, Coombs, R
Format: Journal article
Language:English
Published: 1994