Differential confounding of rare and common variants in spatially structured populations

Well-powered genome-wide association studies, now made possible through advances in technology and large-scale collaborative projects, promise to characterize the contribution of rare variants to complex traits and disease. However, while population structure is a known confounder of association stu...

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Bibliographic Details
Main Authors: Mathieson, I, McVean, G
Format: Journal article
Language:English
Published: 2012