A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.

We have performed a metabolite quantitative trait locus (mQTL) study of the (1)H nuclear magnetic resonance spectroscopy ((1)H NMR) metabolome in humans, building on recent targeted knowledge of genetic drivers of metabolic regulation. Urine and plasma samples were collected from two cohorts of indi...

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Bibliographic Details
Main Authors:	Nicholson, G, Rantalainen, M, Li, J, Maher, A, Malmodin, D, Ahmadi, K, Faber, J, Barrett, A, Min, J, Rayner, N, Toft, H, Krestyaninova, M, Viksna, J, Neogi, S, Dumas, M, Sarkans, U, Donnelly, P, Illig, T, Adamski, J, Suhre, K, Allen, M, Zondervan, K, Spector, T, Nicholson, J, Lindon, J, Baunsgaard, D, Holmes, E, McCarthy, M, Holmes, C
Format:	Journal article
Language:	English
Published:	Public Library of Science 2011

A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.

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