Evidence for adaptive functional changes in the cerebral cortex with axonal injury from multiple sclerosis.
Axonal injury occurs even in the earliest stages of multiple sclerosis. Magnetic resonance spectroscopic imaging (MRSI) measurements of brain N:-acetylaspartate (NAA), a marker of axonal integrity, show that this axonal injury can occur even in the absence of clinically evident functional impairment...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2000
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