Sperm express a Ca2+-regulated NAADP synthase.

NAADP (nicotinic acid-adenine dinucleotide phosphate), the most potent Ca2+-mobilizing second messenger, is active in a wide range of organisms and cell types. Until now, all NAADP-producing enzymes have been thought to be members of the ADP-ribosyl cyclase family. ADP-ribosyl cyclases exhibit promi...

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Bibliographic Details
Main Authors: Vasudevan, SR, Galione, A, Churchill, G
Format: Journal article
Language:English
Published: 2008