The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery

The ongoing explosion in genomics data has long since outpaced the capacity of conventional biochemical methodology to verify the large number of hypotheses that emerge from the analysis of such data. In contrast, it is still a gold-standard for early phenotypic validation towards small-molecule dru...

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Những tác giả chính: Bradley, A, Echalier-Glazer, A, Fairhead, M, Strain-Damerell, C, Brennan, P, Bullock, A, Burgess-Brown, N, Carpenter, E, Gileadi, O, Marsden, B, Lee, W, Yue, W, Bountra, C, von Delft, F
Định dạng: Journal article
Được phát hành: Portland Press 2017