When should factorial designs be used for late-phase randomised controlled trials?
<p><b>Background</b></p> A 2×2 factorial design evaluates two interventions (A versus control and B versus control) by randomising to control, A-only, B-only or both A and B together. Extended factorial designs are also possible (e.g. 3×3 or 2×2×2). Factorial designs often re...
Main Authors: | White, IR, Szubert, AJ, Choodari-Oskooei, B, Walker, AS, Parmar, MKB |
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Format: | Journal article |
Language: | English |
Published: |
SAGE Publications
2023
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