The emerging role of Mule and ARF in the regulation of base excision repair.

The emerging role of Mule and ARF in the regulation of base excision repair.

Εμφάνιση άλλων εκδόσεων (1)

The ARF (Alternative Reading Frame) protein is encoded in the Ink4a locus of human chromosome 9 that is frequently mutated in cancer cells. It was recently demonstrated that ARF is induced in response to DNA damage and inhibits, by direct interaction, the E3 ubiquitin ligase Mule that regulates p53...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Khoronenkova, S, Dianov, G
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2011

Παρόμοια τεκμήρια

The emerging role of Mule and ARF in the regulation of base excision repair
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Έκδοση: (2011)

Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
ανά: Parsons, J, κ.ά.
Έκδοση: (2009)

USP7S-dependent inactivation of Mule regulates DNA damage signalling and repair.
ανά: Khoronenkova, S, κ.ά.
Έκδοση: (2013)

ARF induction in response to DNA strand breaks is regulated by PARP1
ανά: Orlando, G, κ.ά.
Έκδοση: (2013)

USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β.
ανά: Parsons, J, κ.ά.
Έκδοση: (2011)

Base excision repair targets for cancer therapy.
ανά: Dianov, G
Έκδοση: (2011)

Monitoring base excision repair by in vitro assays.
ανά: Dianov, G
Έκδοση: (2003)

Regulation of USP7/HAUSP in response to DNA damage: yet another role for ATM.
ανά: Khoronenkova, S, κ.ά.
Έκδοση: (2012)

Mammalian base excision repair: the forgotten archangel.
ανά: Dianov, G, κ.ά.
Έκδοση: (2013)

Co-ordination of base excision repair and genome stability.
ανά: Parsons, J, κ.ά.
Έκδοση: (2013)

Targeting base excision repair to improve cancer therapies.
ανά: Sharma, R, κ.ά.
Έκδοση: (2007)

DNA repair fidelity of base excision repair pathways in human cell extracts.
ανά: Zhang, Q, κ.ά.
Έκδοση: (2005)

In vitro base excision repair using mammalian cell extracts.
ανά: Parsons, J, κ.ά.
Έκδοση: (2012)

Base excision repair fidelity in normal and cancer cells.
ανά: Chan, K, κ.ά.
Έκδοση: (2006)

Orchestration of base excision repair by controlling the rates of enzymatic activities.
ανά: Allinson, S, κ.ά.
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USP7/HAUSP stimulates repair of oxidative DNA lesions.
ανά: Khoronenkova, S, κ.ά.
Έκδοση: (2011)

DNA base excision repair: the Achilles' heel of tumour cells and their microenvironment?
ανά: Poletto, M, κ.ά.
Έκδοση: (2017)

Exchangeability of mammalian DNA ligases between base excision repair pathways.
ανά: Sleeth, K, κ.ά.
Έκδοση: (2004)

Monitoring base excision repair proteins on damaged DNA using human cell extracts.
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Έκδοση: (2004)

p53 coordinates base excision repair to prevent genomic instability
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CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.
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XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.
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DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair.
ανά: Parsons, J, κ.ά.
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Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability
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Έκδοση: (2015)

Isolation of a small molecule inhibitor of DNA base excision repair.
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Overexpression of DNA polymerase beta results in an increased rate of frameshift mutations during base excision repair.
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The Brick Mule
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Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells
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Regulators and Effectors of Arf GTPases in Neutrophils
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Regulation of DNA repair by ubiquitylation.
ανά: Dianov, G, κ.ά.
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DNA Damage and Base Excision Repair in Mitochondria and Their Role in Aging
ανά: Ricardo Gredilla
Έκδοση: (2011-01-01)

The Domino Effect: Nucleosome Dynamics and the Regulation of Base Excision Repair Enzymes
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Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.
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