Coupled RNA processing and transcription of intergenic primary microRNAs.

Coupled RNA processing and transcription of intergenic primary microRNAs.

The first step in microRNA (miRNA) biogenesis occurs in the nucleus and is mediated by the Microprocessor complex containing the RNase III-like enzyme Drosha and its cofactor DGCR8. Here we show that the 5'-->3' exonuclease Xrn2 associates with independently transcribed miRNAs and,...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Ballarino, M, Pagano, F, Girardi, E, Morlando, M, Cacchiarelli, D, Marchioni, M, Proudfoot, N, Bozzoni, I
Natura:	Journal article
Lingua:	English
Pubblicazione:	2009

Documenti analoghi

Primary microRNA transcripts are processed co-transcriptionally.
di: Morlando, M, et al.
Pubblicazione: (2008)

Primary microRNA transcripts are processed co-transcriptionally.
di: Morlando, M, et al.
Pubblicazione: (2008)

Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs
di: Dhir, A, et al.
Pubblicazione: (2015)

Mechanisms of action of intranuclear microRNAs. Part 1. Influence of microRNA on transcription
di: A.E. Abaturov, et al.
Pubblicazione: (2021-12-01)

Transcription and polyadenylation in a short human intergenic region
di: Brackenridge, S, et al.
Pubblicazione: (1997)

Transcription and polyadenylation in a short human intergenic region.
di: Brackenridge, S, et al.
Pubblicazione: (1997)

Intergenic transcription and transinduction of the human beta-globin locus.
di: Ashe, H, et al.
Pubblicazione: (1997)

Intergenic transcription in the human beta-globin gene cluster.
di: Plant, K, et al.
Pubblicazione: (2001)

Data on microRNAs and microRNA-targeted mRNAs in Xenopus ectoderm
di: Vrutant V. Shah, et al.
Pubblicazione: (2016-12-01)

High throughput approaches reveal splicing of primary microRNA transcripts and tissue specific expression of mature microRNAs in <it>Vitis vinifera</it>
di: Policriti Alberto, et al.
Pubblicazione: (2009-11-01)

Evidence for antisense transcription associated with microRNA target mRNAs in Arabidopsis.
di: Qing-Jun Luo, et al.
Pubblicazione: (2009-04-01)

Correction: High throughput approaches reveal splicing of primary microRNA transcripts and tissue specific expression of mature microRNAs in <it>Vitis vinifera</it>
di: Policriti Alberto, et al.
Pubblicazione: (2010-02-01)

Mechanisms of action of cytoplasmic microRNAs. Part 1. Mechanisms of interaction of microRNA and mRNA molecules. Influence of microRNAs on translation
di: A.E. Abaturov, et al.
Pubblicazione: (2022-04-01)

Identifying microRNAs and transcript targets in Jatropha seeds.
di: Vanessa Galli, et al.
Pubblicazione: (2014-01-01)

Cellular localization and processing of primary transcripts of exonic microRNAs.
di: Izabella Slezak-Prochazka, et al.
Pubblicazione: (2013-01-01)

Pathological microRNAs in acute cardiovascular diseases and microRNA therapeutics
di: Syed Salman Ali, et al.
Pubblicazione: (2016-01-01)

Post-transcriptional regulation of amyloid precursor protein by microRNAs and RNA binding proteins
di: Francesca Ruberti, et al.
Pubblicazione: (2010-11-01)

Intergenic RNA mainly derives from nascent transcripts of known genes
di: Federico Agostini, et al.
Pubblicazione: (2021-05-01)

On the Importance of Host MicroRNAs During Viral Infection
di: Erika Girardi, et al.
Pubblicazione: (2018-10-01)

Transcription of the major neurospora crassa microRNA-like small RNAs relies on RNA polymerase III.
di: Qiuying Yang, et al.
Pubblicazione: (2013-01-01)

Transcription of microRNAs is regulated by developmental signaling pathways and transcription factors
di: Malcolm Arnott, et al.
Pubblicazione: (2024-04-01)

Coregulation of transcription factors and microRNAs in human transcriptional regulatory network
di: Chen Shui-Tein, et al.
Pubblicazione: (2011-02-01)

Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501
di: Maria Goldberg, et al.
Pubblicazione: (2021-10-01)

Analysis of microRNAs and the microRNA-messengerRNA regulatory network in chronic alcohol exposure
di: Ailin Du, et al.
Pubblicazione: (2024-08-01)

The Long Intergenic Noncoding RNA 00707 Sponges MicroRNA-613 (miR-613) to Promote Proliferation and Invasion of Gliomas
di: Handong Liu MM, et al.
Pubblicazione: (2020-10-01)

Functional Implications of RNA Splicing for Human Long Intergenic Noncoding RNAs
di: Feng-Chi Chen, et al.
Pubblicazione: (2014-01-01)

Functional Implications of RNA Splicing for Human Long Intergenic Noncoding RNAs
di: Feng-Chi Chen, et al.
Pubblicazione: (2014-12-01)

Dicer-dependent turnover of intergenic transcripts from the human beta-globin gene cluster.
di: Haussecker, D, et al.
Pubblicazione: (2005)

Long intergenic non-coding RNAs (LincRNAs) identified by RNA-seq in breast cancer.
di: Xianfeng Ding, et al.
Pubblicazione: (2014-01-01)

Mammalian microRNAs: post-transcriptional gene regulation in RNA virus infection and therapeutic applications
di: Yasuko Tsunetsugu-Yokota, et al.
Pubblicazione: (2010-10-01)

The Menu of Features that Define Primary MicroRNAs and Enable De Novo Design of MicroRNA Genes
di: Fang, Wenwen, et al.
Pubblicazione: (2018)

Integration of MicroRNA, mRNA, and Protein Expression Data for the Identification of Cancer-Related MicroRNAs.
di: Jiyoun Seo, et al.
Pubblicazione: (2017-01-01)

Long non-coding RNAs: new players in hematopoiesis and leukemia
di: Mariangela eMorlando, et al.
Pubblicazione: (2015-04-01)

Identification of common carp (<it>Cyprinus carpio</it>) microRNAs and microRNA-related SNPs
di: Zhu Ya-Ping, et al.
Pubblicazione: (2012-08-01)

Bringing MicroRNAs to Light: Methods for MicroRNA Quantification and Visualization in Live Cells
di: Tarana Siddika, et al.
Pubblicazione: (2021-01-01)

Beyond circulating microRNA biomarkers: Urinary microRNAs in ovarian and breast cancer
di: Maria Luisa Gasparri, et al.
Pubblicazione: (2017-04-01)

microRNA Profiling of Amniotic Fluid: Evidence of Synergy of microRNAs in Fetal Development.
di: Tingting Sun, et al.
Pubblicazione: (2016-01-01)

Alternative processing of primary microRNA transcripts by Drosha generates 5' end variation of mature microRNA.
di: Haoquan Wu, et al.
Pubblicazione: (2009-10-01)

A longitudinal study defined circulating microRNAs as reliable biomarkers for disease prognosis and progression in ALS human patients
di: Gabriella Dobrowolny, et al.
Pubblicazione: (2021-01-01)

Regulation of a TrkB Alternative Transcript by microRNAs
di: Jenny Wong
Pubblicazione: (2014-09-01)