SCANPS: a web server for iterative protein sequence database searching by dynamic programing, with display in a hierarchical SCOP browser.

SCANPS performs iterative profile searching similar to PSI-BLAST but with full dynamic programing on each cycle and on-the-fly estimation of significance. This combination gives good sensitivity and selectivity that outperforms PSI-BLAST in domain-searching benchmarks. Although computationally expen...

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Bibliographic Details
Main Authors: Walsh, T, Webber, C, Searle, S, Sturrock, S, Barton, G
Format: Journal article
Language:English
Published: 2008