The light chain IgLV3-21 defines a new poor prognostic subgroup in chronic lymphocytic leukemia: Results of a multicenter study
<p><strong>Purpose:</strong> Unmutated (UM) immunoglobulin heavy chain variable region (IgHV) status or IgHV3-21 gene usage is associated with poor prognosis in chronic lymphocytic leukemia (CLL) patients. Interestingly, IgHV3-21 is often co-expressed with light chain IgLV3-21, whi...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
American Association for Cancer Research
2018
|