The light chain IgLV3-21 defines a new poor prognostic subgroup in chronic lymphocytic leukemia: Results of a multicenter study

The light chain IgLV3-21 defines a new poor prognostic subgroup in chronic lymphocytic leukemia: Results of a multicenter study

<p><strong>Purpose:</strong> Unmutated (UM) immunoglobulin heavy chain variable region (IgHV) status or IgHV3-21 gene usage is associated with poor prognosis in chronic lymphocytic leukemia (CLL) patients. Interestingly, IgHV3-21 is often co-expressed with light chain IgLV3-21, whi...

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Main Authors: Stamatopoulos, B, Smith, T, Crompot, E, Pieters, K, Clifford, R, Mraz, M, Robbe, P, Burns, A, Timbs, A, Bruce, D, Hillmen, P, Meuleman, N, Mineur, P, Firescu, R, Maerevoet, M, De Wilde, V, Efira, A, Philippé, J, Verhasselt, B, Offner, F, Sims, D, Heger, A, Dreau, H, Schuh, A
Format: Journal article
Language:English
Published: American Association for Cancer Research 2018

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