Combining regulatory angiogenic gene therapy and virotherapy for the treatment of breast cancer
<p>This thesis describes the design of a virotherapy strategy capable of destroying both breast cancer vasculature and tumour cells, using an oncolytic adenovirus expressing angiogenesis-regulating proteins. Five oncolytic adenoviruses were compared to identify the best virotherapy agent for b...
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Format: | Thesis |
Language: | English |
Published: |
2007
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