Functional annotation of deubiquitinating enzymes using RNA interference.

Protein ubiquitination is a dynamic process, depending on a tightly regulated balance between the activity of ubiquitin ligases and their antagonists, the ubiquitin-specific proteases or deubiquitinating enzymes. The family of ubiquitin ligases has been studied intensively and it is well established...

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Bibliographic Details
Main Authors: Dirac, A, Nijman, S, Brummelkamp, T, Bernards, R
Format: Journal article
Language:English
Published: 2005