Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.
Recognition of microbial components by germ-line encoded pattern recognition receptors (PRR) initiates immune responses to infectious agents. We and others have proposed that pairs or sets of PRR mediate host immunity. One such pair comprises the fungal beta-glucan receptor, Dectin-1, which collabor...
Main Authors: | , , , , , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2008
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