Mathematical modelling of metabolism and acidity in cancer

<p>Human cancers exhibit the common phenotype of elevated glycolytic metabolism, which causes acidification of the tissue microenvironment and may facilitate tumour invasion. In this thesis, we use mathematical models to address a series of open problems underlying the glycolytic tumour phenot...

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Bibliographic Details
Main Author: McGillen, J
Other Authors: Maini, P
Format: Thesis
Language:English
Published: 2014
Subjects: