Mathematical modelling of metabolism and acidity in cancer

Mathematical modelling of metabolism and acidity in cancer

<p>Human cancers exhibit the common phenotype of elevated glycolytic metabolism, which causes acidification of the tissue microenvironment and may facilitate tumour invasion. In this thesis, we use mathematical models to address a series of open problems underlying the glycolytic tumour phenot...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter:	McGillen, J
Andre forfattere:	Maini, P
Format:	Thesis
Sprog:	English
Udgivet:	2014
Fag:	Metabolism Mathematical biology Oncology Approximations and expansions Biology and other natural sciences (mathematics) Partial differential equations Tumours Mathematics

Lignende værker

Mathematical modelling of flow and transport phenomena in tissue engineering
af: Pearson, N
Udgivet: (2014)

In silico modelling of tumour-induced angiogenesis
af: Connor, A
Udgivet: (2014)

Comparing stochastic discrete and deterministic continuum models of cell migration
af: Yates, C
Udgivet: (2011)

Mathematical and computational modelling of tissue engineered bone in a hydrostatic bioreactor
af: Leonard, KHL
Udgivet: (2014)

Mathematical models of the retina in health and disease
af: Roberts, P
Udgivet: (2015)

Mathematical approaches to modelling healing of full thickness circular skin wounds
af: Bowden, L
Udgivet: (2015)

The buckling of capillaries in tumours
af: MacLaurin, J
Udgivet: (2011)

Mathematical modelling of Centrosomin incorporation in Drosophila centrosomes
af: Bakshi, S
Udgivet: (2013)

Spatiotemporal behaviour of stochastic and continuum models for biological signalling on stationary and growing domains
af: Woolley, T, et al.
Udgivet: (2012)

A fictitious domain approach for hybrid simulations of eukaryotic chemotaxis
af: Seguis, J
Udgivet: (2013)

Modelling the transition from channel-veins to PSBs in the early stage of fatigue tests
af: Zhu, Y
Udgivet: (2012)

Towards a computational model of the colonic crypt with a realistic, deformable geometry
af: Dunn, S
Udgivet: (2011)

Parameter recovery in AC solution-phase voltammetry and a consideration of some issues arising when applied to surface-confined reactions
af: Morris, GP
Udgivet: (2014)

Efficient numerical methods for ultrasound elastography
af: Squires, T, et al.
Udgivet: (2012)

Application of software engineering methodologies to the development of mathematical biological models
af: Gill, MS
Udgivet: (2013)

Cell fate mechanisms in colorectal cancer
af: Kay, SK
Udgivet: (2014)

Mathematical evolutionary epidemiology: limited epitopes, evolution of strain structures and age-specificity
af: Cherif, A
Udgivet: (2015)

Computational methods for the estimation of cardiac electrophysiological conduction parameters in a patient specific setting
af: Wallman, K
Udgivet: (2013)

Exponential asymptotics in unsteady and three-dimensional flows
af: Lustri, C, et al.
Udgivet: (2013)

On two-phase flow models for cell motility
af: Kimpton, LS
Udgivet: (2013)

Mathematical models of cranial neural crest cell migration
af: Dyson, L
Udgivet: (2013)

Antiangiogenic Therapy Efficacy Can Be Tumor-Size Dependent, as Mathematical Modeling Suggests
af: Maxim Kuznetsov, et al.
Udgivet: (2024-01-01)

Genomic imprinting and sex allocation
af: Wild, G, et al.
Udgivet: (2009)

A sex allocation theory for vertebrates: combining local resource competition and condition-dependent allocation
af: Wild, G, et al.
Udgivet: (2007)

Flow and nutrient transport problems in rotating bioreactor systems
af: Dalwadi, M, et al.
Udgivet: (2014)

Mathematical modelling of human sperm motility
af: Gadelha, H
Udgivet: (2012)

Probabilistic bias in genotype-phenotype maps
af: Dingle, K
Udgivet: (2014)

Automatic simplification of differential equation models by a posteriori analysis
af: Maybank, P
Udgivet: (2012)

Excluded-volume effects in stochastic models of diffusion
af: Bruna, M
Udgivet: (2012)

Expansion methods for high-dimensional PDEs in finance
af: Wissmann, R
Udgivet: (2015)

Competition and cooperation in host-associated microbial communities: insights from computational and mathematical models
af: Schluter, J
Udgivet: (2014)

Tumour-stromal interactions in cancer progression and drug resistance
af: Picco, N
Udgivet: (2016)

Large-scale layered systems and synthetic biology: model reduction and decomposition
af: Prescott, T, et al.
Udgivet: (2014)

Effective design of marine reserves: incorporating alongshore currents, size structure, and uncertainty
af: Reimer, J
Udgivet: (2013)

Modelling of calcium handling in genetically modified mice
af: Li, L
Udgivet: (2011)

Mathematical modelling of compaction and diagenesis in sedimentary basins
af: Yang, X
Udgivet: (1997)

Impact of tissue microstructure on a model of cardiac electromechanics based on MRI data
af: Carapella, V
Udgivet: (2013)

Mathematical modelling of oxygen transport in skeletal and cardiac muscles
af: Alshammari, A
Udgivet: (2014)

Mathematical modelling of oncolytic virotherapy
af: Shabala, A
Udgivet: (2013)

The evolution of cooperation, especially in humans
af: El Mouden, C
Udgivet: (2011)