Molecular insights into substrate specificity of prostate specific antigen through structural modeling.

Prostate Specific Antigen's (PSA) role as a biomarker for prostate cancer is well established but the physiological role of its serine protease activity in the pathobiology of normal prostate and prostate carcinogenesis remains largely unknown. In light of recent studies that implicate PSA'...

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Bibliographic Details
Main Authors: Singh, P, LeBeau, A, Lilja, H, Denmeade, SR, Isaacs, J
Format: Journal article
Language:English
Published: 2009