Finding the missing heritability of complex diseases.

Finding the missing heritability of complex diseases.

Genome-wide association studies have identified hundreds of genetic variants associated with complex human diseases and traits, and have provided valuable insights into their genetic architecture. Most variants identified so far confer relatively small increments in risk, and explain only a small pr...

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Detalhes bibliográficos
Principais autores: Manolio, T, Collins, F, Cox, N, Goldstein, D, Hindorff, L, Hunter, D, McCarthy, M, Ramos, E, Cardon, L, Chakravarti, A, Cho, J, Guttmacher, A, Kong, A, Kruglyak, L, Mardis, E, Rotimi, C, Slatkin, M, Valle, D, Whittemore, A, Boehnke, M, Clark, A, Eichler, E, Gibson, G, Haines, J, Mackay, T
Formato: Journal article
Idioma:English
Publicado em: 2009

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