A global sensitivity tool for cardiac cell modeling: Application to ionic current balance and hypertrophic signaling.

Cardiovascular diseases are the major cause of death in the developed countries. Identifying key cellular processes involved in generation of the electrical signal and in regulation of signal transduction pathways is essential for unraveling the underlying mechanisms of heart rhythm behavior. Comput...

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Autors principals: Sher, A, Cooling, M, Bethwaite, B, Tan, J, Peachey, T, Enticott, C, Garic, S, Gavaghan, D, Noble, D, Abramson, D, Crampin, E
Format: Journal article
Idioma:English
Publicat: 2010