Probing the distinct chemosensitivity of Plasmodium vivax liver stage parasites and demonstration of 8-aminoquinoline radical cure activity in vitro

Improved control of Plasmodium vivax malaria can be achieved with the discovery of new antimalarials with radical cure efficacy, including prevention of relapse caused by hypnozoites residing in the liver of patients. We screened several compound libraries against P. vivax liver stages, including 15...

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Autors principals: Maher, SP, Vantaux, A, Chaumeau, V, Chua, ACY, Cooper, CA, Andolina, C, Péneau, J, Rouillier, M, Rizopoulos, Z, Phal, S, Piv, E, Vong, C, Phen, S, Chhin, C, Tat, B, Ouk, S, Doeurk, B, Kim, S, Suriyakan, S, Kittiphanakun, P, Awuku, NA, Conway, AJ, Jiang, RHY, Russell, B, Bifani, P, Campo, B, Nosten, F, Witkowski, B, Kyle, DE
Format: Journal article
Idioma:English
Publicat: Springer Nature 2021