Interdependence of CD3-Ti and CD2 activation pathways in human T lymphocytes.
Human T lymphocytes can be activated through either the antigen/MHC receptor complex T3-Ti (CD3-Ti) or the T11 (CD2) molecule to proliferate via an IL-2 dependent mechanism. To investigate the relationship of these pathways to one another, we generated and characterized Jurkat mutants which selectiv...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1988
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