DNA copy-number measurement of genome replication dynamics by high-throughput sequencing: the sort-seq, sync-seq and MFA-seq family.

Genome replication follows a defined temporal programme that can change during cellular differentiation and disease onset. DNA replication results in an increase in DNA copy number that can be measured by high-throughput sequencing. Here we present a protocol to determine genome replication dynamics...

Повний опис

Бібліографічні деталі
Автори: Batrakou, DG, Müller, CA, Wilson, RHC, Nieduszynski, CA
Формат: Journal article
Мова:English
Опубліковано: Nature Research 2020