Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.

Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.

OBJECTIVE: The causal nature of associations between circulating triglycerides, insulin resistance, and type 2 diabetes is unclear. We aimed to use Mendelian randomization to test the hypothesis that raised circulating triglyceride levels causally influence the risk of type 2 diabetes and raise norm...

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Bibliographic Details
Main Authors: De Silva, N, Freathy, R, Palmer, T, Donnelly, L, Luan, J, Gaunt, T, Langenberg, C, Weedon, M, Shields, B, Knight, B, Ward, K, Sandhu, MS, Harbord, R, McCarthy, M, Smith, G, Ebrahim, S, Hattersley, A, Wareham, N, Lawlor, D, Morris, A, Palmer, C, Frayling, T
Format: Journal article
Language:English
Published: 2011

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