Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

Fully activated innate immune cells are required for effective responses to infection, but their prompt deactivation and removal are essential for limiting tissue damage. Here, we have identified a critical role for the prolyl hydroxylase enzyme Phd2 in maintaining the balance between appropriate, p...

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Bibliographic Details
Main Authors:	Sadiku, P, Willson, JA, Dickinson, RS, Murphy, F, Harris, AJ, Lewis, A, Sammut, D, Mirchandani, AS, Ryan, E, Watts, ER, Thompson, AAR, Marriott, HM, Dockrell, DH, Taylor, CT, Schneider, M, Maxwell, PH, Chilvers, ER, Mazzone, M, Moral, V, Pugh, CW, Ratcliffe, PJ, Schofield, CJ, Ghesquiere, B, Carmeliet, P, Whyte, MK, Walmsley, SR
Format:	Journal article
Language:	English
Published:	American Society for Clinical Investigation 2017

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

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