Access to the bicyclic core of isatisine, and an investigation of its antibacterial activity

A chemoselective Dieckmann ring closure using an oxazolidine derived from serine may be used to generate a tetramic acid, the further manipulation of which by reduction and ring closure leads to the bicyclic core of isatisine; depending on the nature of the ring closing electrophile, different diast...

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Bibliographic Details
Main Authors: Matthews, C, Moloney, MG, Thompson, A, Winiarska, H, Winney, H
Format: Journal article
Language:English
Published: 2011