Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer

<p><strong>Background</strong></p> <p>Polygenic hazard scores (PHS) can identify individuals with increased risk of prostate cancer. We estimated the benefit of additional SNPs on performance of a previously validated PHS (PHS46).</p> <p><strong>Mater...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Karunamuni, RA, Huynh-Le, M-P, Fan, CC, Neal, DE, Hamdy, FC, Travis, RC, Mills, IG, Et al.
Kolejni autorzy: UKGPCS collaborators
Format: Journal article
Język:English
Wydane: Springer Nature 2021