Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer

<p><strong>Background</strong></p> <p>Polygenic hazard scores (PHS) can identify individuals with increased risk of prostate cancer. We estimated the benefit of additional SNPs on performance of a previously validated PHS (PHS46).</p> <p><strong>Mater...

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Main Authors: Karunamuni, RA, Huynh-Le, M-P, Fan, CC, Neal, DE, Hamdy, FC, Travis, RC, Mills, IG, Et al.
其他作者: UKGPCS collaborators
格式: Journal article
语言:English
出版: Springer Nature 2021