Site-selective glycosylation of proteins: creating synthetic glycoproteins.

In higher organisms, the functions of many proteins are modulated by post-translational modifications (PTMs). Glycosylation is by far the most diverse of the PTM processes. Natural protein production methods typically produce PTM or glycoform mixtures within which function is difficult to dissect or...

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Autori principali: van Kasteren, S, Kramer, H, Gamblin, D, Davis, B
Natura: Journal article
Lingua:English
Pubblicazione: 2007