New lives for old: evolution of pseudoenzyme function illustrated by iRhoms.
Large-scale sequencing of genomes has revealed that most enzyme families include inactive homologues. These pseudoenzymes are often well conserved, implying a selective pressure to retain them during evolution, and therefore that they have significant function. Mechanistic insights and evolutionary...
| Main Authors: | , |
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| Format: | Journal article |
| Jezik: | English |
| Izdano: |
2012
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