New lives for old: evolution of pseudoenzyme function illustrated by iRhoms.
Large-scale sequencing of genomes has revealed that most enzyme families include inactive homologues. These pseudoenzymes are often well conserved, implying a selective pressure to retain them during evolution, and therefore that they have significant function. Mechanistic insights and evolutionary...
| Main Authors: | , |
|---|---|
| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
2012
|