Stem cell plasticity and niche dynamics in cancer progression

<h4>Objective</h4> <p>Cancer stem cells (CSCs) have been hypothesized to initiate and drive tumor growth and recurrence due to their self-renewal ability. If correct, this hypothesis implies that successful therapy must focus primarily on eradication of this CSC fraction. However,...

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Bibliographic Details
Main Authors: Picco, N, Gatenby, R, Anderson, A
Format: Journal article
Published: Institute of Electrical and Electronics Engineers 2016