The Fidelity of Synaptonemal Complex Assembly Is Regulated by a Signaling Mechanism that Controls Early Meiotic Progression

Proper chromosome segregation during meiosis requires the assembly of the synaptonemal complex (SC) between homologous chromosomes. However, the SC structure itself is indifferent to homology, and poorly understood mechanisms that depend on conserved HORMA-domain proteins prevent ectopic SC assembly...

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Bibliographic Details
Main Authors: Silva, N, Ferrandiz, N, Barroso, C, Tognetti, S, Lightfoot, J, Telecan, O, Encheva, V, Faull, P, Hanni, S, Furger, A, Snijders, A, Speck, C, Martinez-Perez, E
Format: Journal article
Language:English
Published: Cell Press 2014