Hypoxic and pharmacological activation of HIFs inhibits SARS-CoV-2 infection of lung epithelial cells

COVID-19, caused by the novel coronavirus SARS-CoV-2, is a global health issue with more than 1 million fatalities to date. Understanding how host factors modify the viral life cycle could inform susceptibility to viral infection and the design of new therapies. Viral replication is shaped by the ce...

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Bibliographic Details
Main Authors: Wing, P, Keeley, TP, Zhuang, X, Lee, JY, Prange-Barczynska, M, Tsukuda, S, Morgan, SB, Harding, AC, Argles, ILA, Kurlekar, S, Noerenberg, M, Thompson, CP, Huang, K-YA, Balfe, P, Watashi, K, Castello, A, Hinks, TSC, James, W, Ratcliffe, PJ, Davis, I, Hodson, EJ, Bishop, T, McKeating, J
Format: Journal article
Language:English
Published: Cell Press 2021